TFIP11

Name

tuftelin interacting protein 11

Type

protein-coding

Position

26,490,722–26,512,505 (−)

Aliases

NTR1, STIP, STIP-1, Spp382, TIP39, bK445C9.6

Ensembl

ENSG00000100109

RefSeq RNA

NM_001008697.3, NM_001346857.2, NM_001346858.2, NM_001346859.2, NM_001346861.2

RefSeq protein

NP_001008697.1, NP_001333786.1, NP_001333787.1, NP_001333788.1, NP_001333790.1

This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016].

via MyGene.info

Gene · Ensembl

tuftelin interacting protein 11

Symbol

TFIP11

Biotype

Protein coding

Organism

Homo sapiens

Location

22:26,490,722-26,512,505

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0