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timonacic

Structure via PubChem · Public domain (PubChem)

EntityQ23637400· pop 5· linked from 5 articles

Also known as Thiazolidinecarboxylic acid, DL-Thiaproline, DL-Thiazolidinecarboxylic acid, 4-Thiazolidinecarboxylic acid, Thiazolidine-4-carboxylic acid, Thiaproline, 4-Carboxythiazolidine

Thioproline is a nonproteinogenic amino acid with the formula , although it crystallizes as the zwitterion . It consists of a 1,3-thiazolidine ring ( ) substituted with a carboxylic acid. It is synthesized by reaction of formaldehyde and cysteine. It occurs in nature, but rarely. It forms a coordination complex with cobalt.

Chemical data

Formula
C4H7NO2S
Molecular weight
133.17 g/mol
IUPAC name
1,3-thiazolidine-4-carboxylic acid
SMILES
C1C(NCS1)C(=O)O
InChIKey
DZLNHFMRPBPULJ-UHFFFAOYSA-N
XLogP
-2.3
Polar surface area
74.6 Ų
H-bond donors
2
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
133.02
Show 7 more facts
found in taxon
Lentinula edodes
subject has role
antioxidant
canonical SMILES
C1C(NCS1)C(=O)O
chemical formula
C₄H₇NO₂S
pKa
1.51
World Health Organisation international non-proprietary name
timonacic
Commons category
1,3-Thiazolidine-4-carboxylic acid
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

1 sections
Contents
  • References

Thioproline is a nonproteinogenic amino acid with the formula , although it crystallizes as the zwitterion . It consists of a 1,3-thiazolidine ring ( ) substituted with a carboxylic acid. It is synthesized by reaction of formaldehyde and cysteine. It occurs in nature, but rarely. It forms a coordination complex with cobalt.

== References ==

Excerpted from Wikipedia’s “timonacic” article, available under the CC BY-SA 4.0 licence.

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