TINAG
Sign in to saveAlso known as TIN-AG, tubulointerstitial nephritis antigen
Tubulointerstitial nephritis antigen is a protein that in humans is encoded by the TINAG gene.
Gene data
TINAG- Name
- tubulointerstitial nephritis antigen
- Type
- protein-coding
- Position
- 54,307,859–54,390,142 (+)
- Aliases
- TIN-AG
- Ensembl
- ENSG00000137251
- RefSeq RNA
- NM_014464.4, XM_006715062.3, XM_011514497.3, XM_017010745.2, XM_017010746.2
- RefSeq protein
- NP_055279.3, XP_006715125.1, XP_011512799.1, XP_016866234.1, XP_016866235.1
This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis. [provided by RefSeq, Nov 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
tubulointerstitial nephritis antigen
- Symbol
- TINAG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:54,307,859-54,390,142
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 8082
- exact match
- identifiers.org/ncbigene/27283
- genomic end
- 54390142
- genomic start
- 54172657
- chromosome
- human chromosome 6
- cytogenetic location
- 6p12.1
- expressed in
- gallbladder
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Tubulointerstitial nephritis antigen is a protein that in humans is encoded by the TINAG gene.
TINAG is a basement membrane glycoprotein initially identified as a target of antibodies in some forms of immunologically mediated tubulointerstitial nephritis.[supplied by OMIM]
Excerpted from Wikipedia’s “TINAG” article, available under the CC BY-SA 4.0 licence.