TMBIM6
Sign in to saveAlso known as BAXI1, BI-1, TEGT, transmembrane BAX inhibitor motif containing 6
Bax inhibitor 1 is a protein that in humans is encoded by the TMBIM6 gene.
Gene data
TMBIM6- Name
- transmembrane BAX inhibitor motif containing 6
- Type
- protein-coding
- Position
- 49,707,725–49,764,935 (+)
- Aliases
- BAXI1, BI-1, TEGT
- Ensembl
- ENSG00000139644
- RefSeq RNA
- NM_001098576.2, NM_001414462.1, NM_001414463.1, NM_001414464.1, NM_003217.3
- RefSeq protein
- NP_001092046.1, NP_001401391.1, NP_001401392.1, NP_001401393.1, NP_003208.2
Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process; negative regulation of intrinsic apoptotic signaling pathway; and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
transmembrane BAX inhibitor motif containing 6
- Symbol
- TMBIM6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:49,707,725-49,764,935
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 2419
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7009
- genomic end
- 50158717
- genomic start
- 50101508
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.12
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Bax inhibitor 1 is a protein that in humans is encoded by the TMBIM6 gene.
==References==
Excerpted from Wikipedia’s “TMBIM6” article, available under the CC BY-SA 4.0 licence.