TMED10
Sign in to saveAlso known as P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23, p24d1, transmembrane p24 trafficking protein 10
Transmembrane emp24 domain-containing protein 10 is a protein that in humans is encoded by the TMED10 gene.
Gene data
TMED10- Name
- transmembrane p24 trafficking protein 10
- Type
- protein-coding
- Position
- 75,131,106–75,176,652 (−)
- Aliases
- P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23, p24d1
- Ensembl
- ENSG00000170348
- RefSeq RNA
- NM_006827.6
- RefSeq protein
- NP_006818.3
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
transmembrane p24 trafficking protein 10
- Symbol
- TMED10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:75,131,106-75,176,652
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Transmembrane emp24 domain-containing protein 10 is a protein that in humans is encoded by the TMED10 gene.
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Excerpted from Wikipedia’s “TMED10” article, available under the CC BY-SA 4.0 licence.