TMEM176B

Also known as LR8, MS4B2, transmembrane protein 176B

Transmembrane Protein 176B, or TMEM176B is a transmembrane protein that in humans is encoded by the TMEM176B gene. It is thought to play a role in the process of maturation of dendritic cells.

Gene data

TMEM176B

Name: transmembrane protein 176B
Type: protein-coding
Position: 150,789,455–150,823,877 (−)
Aliases: LR8, MS4B2
Ensembl: ENSG00000106565
RefSeq RNA: NM_001101311.2, NM_001101312.2, NM_001101313.1, NM_001101314.2, NM_001362691.2
RefSeq protein: NP_001094781.1, NP_001094782.1, NP_001094784.1, NP_001349620.1, NP_001349621.1

Predicted to be involved in negative regulation of dendritic cell differentiation. Predicted to be located in nuclear membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

animal organ morphogenesis negative regulation of dendritic cell differentiation

Molecular function

protein binding

Cellular component

membrane nuclear membrane

via MyGene.info

Gene · Ensembl

transmembrane protein 176B

Symbol: TMEM176B
Biotype: Protein coding
Organism: Homo sapiens
Location: 7:150,789,455-150,823,877
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 8521
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/28959
genomic end: 150498448
genomic start: 150488373
chromosome: human chromosome 7
cytogenetic location: 7q36.1
expressed in: decidua

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Encyclopedic overview

19 sections

Contents

Gene
Location
Gene
Expression
Transcript variants
Homology
Paralogs
Orthologs
Homologs
Protein
Domains
Secondary structure
Subcellular localization
Protein-protein interactions
Regulation
Gene
Protein
Clinical significance
References

Transmembrane Protein 176B, or TMEM176B is a transmembrane protein that in humans is encoded by the TMEM176B gene. It is thought to play a role in the process of maturation of dendritic cells.

== Gene ==

Excerpted from Wikipedia’s “TMEM176B” article, available under the CC BY-SA 4.0 licence.

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