TNFAIP8L2
Sign in to saveAlso known as TIPE2, TNF alpha induced protein 8 like 2
TNF alpha induced protein 8 like 2 (TNFAIP8L2), also known as TIPE2, is a protein that in humans is encoded by the TNFAIP8L2 gene. It is preferentially expressed in human myeloid cell types and serves as an immune checkpoint regulator of inflammation and metabolism.
Gene data
TNFAIP8L2- Name
- TNF alpha induced protein 8 like 2
- Type
- protein-coding
- Aliases
- TIPE2
Predicted to be involved in negative regulation of T cell activation and negative regulation of inflammatory response. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
TNF alpha induced protein 8 like 2
- Symbol
- TNFAIP8L2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:151,156,621-151,160,255
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 56998
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79626
- genomic end
- 151132225
- genomic start
- 151156649
- chromosome
- human chromosome 1
- cytogenetic location
- 1q21.3
- expressed in
- trabecular bone
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Structure
- Clinical significance
- References
TNF alpha induced protein 8 like 2 (TNFAIP8L2), also known as TIPE2, is a protein that in humans is encoded by the TNFAIP8L2 gene. It is preferentially expressed in human myeloid cell types and serves as an immune checkpoint regulator of inflammation and metabolism.
== Function ==
Excerpted from Wikipedia’s “TNFAIP8L2” article, available under the CC BY-SA 4.0 licence.