TNPO3
Sign in to saveAlso known as IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2, TRNSR, transportin 3, LGMDD2
Transportin-3 is a protein that in humans is encoded by the TNPO3 gene.
Gene data
TNPO3- Name
- transportin 3
- Type
- protein-coding
- Position
- 128,954,180–129,055,208 (−)
- Aliases
- IPO12, LGMD1F, LGMDD2, MTR10A, TRN-SR, TRN-SR2, TRNSR
- Ensembl
- ENSG00000064419
- RefSeq RNA
- NM_001191028.3, NM_001382216.1, NM_001382217.1, NM_001382218.1, NM_001382219.1
- RefSeq protein
- NP_001177957.2, NP_001369145.1, NP_001369146.1, NP_001369147.1, NP_001369148.1
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Several protein-coding and non-coding transcript variants have been found for this gene. [provided by RefSeq, Apr 2020].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
transportin 3
- Symbol
- TNPO3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:128,954,180-129,055,208
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- 4c0p transportin3.png
Show 8 more facts
- HomoloGene ID
- 40848
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23534
- genomic start
- 128594948
- chromosome
- human chromosome 7
- genomic end
- 128695198
- cytogenetic location
- 7q32.1
- expressed in
- beta cell
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Transportin-3 is a protein that in humans is encoded by the TNPO3 gene.
== Function ==
Excerpted from Wikipedia’s “TNPO3” article, available under the CC BY-SA 4.0 licence.