Toxodontidae

thumb|right|Xotodon sp. skull at the Museum für Naturkunde, Berlin

Toxodontidae (from Ancient Greek τόξον (tóxon), meaning "bow", and ὀδούς (odoús), meaning "tooth") is an extinct family of notoungulate mammals, known from the Oligocene to the Holocene (11,000 BP) of South America, with one genus, Mixotoxodon, also known from the Pleistocene of Central America and southern North America (as far north as Texas). Member of the family were medium to large-sized, ranging from around in Nesodon to in Toxodon, and had medium to high-crowned dentition, which in derived members of the group evolved into ever-growing cheek teeth.