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EntityQ2747851· pop 5· linked from 3 articles

tricaprylin

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Also known as trioctanoylglyceride, Glycerol trioctanoin, Tricapryloylglycerol, Octanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester, Glycerin tricaprylate, Tricaprylyl glycerin, TG(8:0/8:0/8:0), Glycerol tricaprylate

Axona was previously marketed as a medical food for the clinical dietary management of the impairment of metabolic processes associated with mild to moderate Alzheimer's disease. It is a proprietary formulation of fractionated palm kernel oil (caprylic triglyceride), a medium-chain triglyceride. Cericin, the company that makes Axona, states that during digestion, caprylic triglyceride is broken down into ketones, which provide an alternative energy source for the brain. Its use is based on the idea that the brain's ability to use its normal energy source, glucose, is impaired in Alzheimer's di

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Encyclopedic overview

7 sections
Contents
  • Description
  • Proposed mechanism of action of Axona
  • Clinical trials
  • Sales and marketing
  • Criticism
  • See also
  • References

Axona was previously marketed as a medical food for the clinical dietary management of the impairment of metabolic processes associated with mild to moderate Alzheimer's disease. It is a proprietary formulation of fractionated palm kernel oil (caprylic triglyceride), a medium-chain triglyceride. Cericin, the company that makes Axona, states that during digestion, caprylic triglyceride is broken down into ketones, which provide an alternative energy source for the brain. Its use is based on the idea that the brain's ability to use its normal energy source, glucose, is impaired in Alzheimer's disease. Axona was first sold in March 2009.

In 2013, US Food and Drug Administration (FDA) determined Axona was misbranded because the product was labeled and marketed as a medical food but does not meet the statutory definition of a medical food. Axona has not been approved by the FDA as a drug to treat Alzheimer's and the efficacy of managing the health of Alzheimer's patients by use of this medical food has been questioned by experts in the field, including the Alzheimer's Association.

Excerpted from Wikipedia’s “tricaprylin” article, available under the CC BY-SA 4.0 licence.

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