Structure via PubChem · Public domain (PubChem)
تریکودرمین
Sign in to saveTrichodermin is a trichothecene. It inhibits protein formation in Euchariotes.
Chemical data
- Formula
- C17H24O4
- Molecular weight
- 292.4 g/mol
- IUPAC name
- [(1S,2R,7R,9R,11R,12S)-1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl] acetate
- SMILES
- CC1=C[C@@H]2[C@](CC1)([C@]3([C@@H](C[C@H]([C@@]34CO4)O2)OC(=O)C)C)C
- InChIKey
- HNEGCRMUYSKRRR-IKIFYQGPSA-N
- XLogP
- 1.8
- Polar surface area
- 48.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
151 papers- Trichodermin, an endophytic fungal sesquiterpene, suppresses colorectal cancer cell migration and invasion by targeting the PKC-ERK-Sp1-CTSV axis.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2025
- Trichodermin Induces G0/G1 Cell Cycle Arrest by Inhibiting c-Myc in Ovarian Cancer Cells and Tumor Xenograft-Bearing Mice.International journal of molecular sciences · 2021
- Trichodermin (4β-acet-oxy-12,13-epoxy-trichothec-9-ene).Acta crystallographica. Section E, Structure reports online · 2008
- Trichodermin inhibits the growth of oral cancer through apoptosis-induced mitochondrial dysfunction and HDAC-2-mediated signaling.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
- Synthesis of Trichodermin Derivatives and Their Antimicrobial and Cytotoxic Activities.Molecules (Basel, Switzerland) · 2019
via PubMed
Wikidata facts
- Mass
- 292.167
Show 3 more facts
- chemical formula
- C₁₇H₂₄O₄
- canonical SMILES
- CC1=CC2C(CC1)(C3(C(CC(C34CO4)O2)OC(=O)C)C)C
- isomeric SMILES
- CC1=C[C@@H]2[C@](CC1)([C@]3([C@@H](C[C@H]([C@@]34CO4)O2)OC(=O)C)C)C
Sources (1)
via Wikidata · CC0