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GeneQ18035540· pop 5· linked from 5 articles

TRIM16

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Also known as EBBP, tripartite motif containing 16

Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16 gene.

Gene data

TRIM16
Name
tripartite motif containing 16
Type
protein-coding
Position
15,627,950–15,684,311 (−)
Aliases
EBBP
Ensembl
ENSG00000221926
RefSeq RNA
NM_001348119.1, NM_001348120.1, NM_001348121.1, NM_001348122.1, NM_001348124.1
RefSeq protein
NP_001335048.1, NP_001335049.1, NP_001335050.1, NP_001335051.1, NP_001335053.1

The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017].

Gene Ontology

via MyGene.info

Gene · Ensembl

tripartite motif containing 16

Symbol
TRIM16
Biotype
Protein coding
Organism
Homo sapiens
Location
17:15,627,950-15,684,311
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 3 more facts
HomoloGene ID
4726
exact match
identifiers.org/ncbigene/10626
found in taxon
Homo sapiens
Sources (3)

via Wikidata · CC0

~5 min read

Encyclopedic overview

7 sections
Contents
  • Structure
  • Function
  • Clinical significance
  • Tumor suppression
  • Cardiac hypertrophy
  • References
  • Further reading

Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16 gene.

This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family.

Excerpted from Wikipedia’s “TRIM16” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0