TRIM22
Sign in to saveAlso known as GPSTAF50, RNF94, STAF50, tripartite motif containing 22
Tripartite motif-containing 22, also known as TRIM22, is a protein which in humans is encoded by the TRIM22 gene.
Gene data
TRIM22- Name
- tripartite motif containing 22
- Type
- protein-coding
- Position
- 5,689,610–5,737,089 (+)
- Aliases
- GPSTAF50, RNF94, STAF50
- Ensembl
- ENSG00000132274
- RefSeq RNA
- NM_001199573.2, NM_006074.5
- RefSeq protein
- NP_001186502.1, NP_006065.2
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein is involved in innate immunity against different DNA and RNA viruses. [provided by RefSeq, Oct 2021].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
tripartite motif containing 22
- Symbol
- TRIM22
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:5,689,610-5,737,089
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 48399
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10346
- genomic end
- 5758319
- genomic start
- 5689697
- chromosome
- human chromosome 11
- cytogenetic location
- 11p15.4
- expressed in
- blood
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- External links
Tripartite motif-containing 22, also known as TRIM22, is a protein which in humans is encoded by the TRIM22 gene.
== Function ==
Excerpted from Wikipedia’s “TRIM22” article, available under the CC BY-SA 4.0 licence.