TSBP1
Sign in to saveAlso known as TSBP, chromosome 6 open reading frame 10, testis expressed basic protein 1, C6orf10
TSBP1 is a protein that in humans is encoded by the TSBP1 gene. TSBP1 was previously known as C6orf10. C6orf10 is an open reading frame on chromosome 6 containing a protein that is ubiquitously expressed at low levels in the adult genome and may play a role during fetal development. C6orf10 has been found to be linked to both neurodegenerative and autoimmune diseases in adults. Expression of this gene is highest in the testis but is also seen in other tissue types such as the brain, lens of the eye and the medulla.
Gene data
TSBP1- Name
- testis expressed basic protein 1
- Type
- protein-coding
- Position
- 32,288,526–32,371,907 (−)
- Aliases
- C6orf10, TSBP
- Ensembl
- ENSG00000232106
- RefSeq RNA
- NM_001286474.2, NM_001286475.2, NM_006781.5, XM_017010182.2, XM_024446307.2
- RefSeq protein
- NP_001273403.1, NP_001273404.1, NP_006772.3, XP_016865671.1, XP_024302075.1
Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
testis expressed basic protein 1
- Symbol
- TSBP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR6_MHC_MANN_CTG1:3,597,691-3,676,908
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~8 min read
Encyclopedic overview
19 sectionsContents
- mRNA Transcript
- Conserved non-coding region
- Protein
- Composition
- Secondary Structure
- Subcellular Localization
- Expression
- Regulation of expression
- Transcriptional
- Transcription factors
- Protein Interactions
- Clinical significance
- Homologs
- [[Homology (biology)|Orthologs]]
- C6orf10 Isoform X4 Orthologs
- Paralogs
- References
- External links
- Further reading
TSBP1 is a protein that in humans is encoded by the TSBP1 gene. TSBP1 was previously known as C6orf10. C6orf10 is an open reading frame on chromosome 6 containing a protein that is ubiquitously expressed at low levels in the adult genome and may play a role during fetal development. C6orf10 has been found to be linked to both neurodegenerative and autoimmune diseases in adults. Expression of this gene is highest in the testis but is also seen in other tissue types such as the brain, lens of the eye and the medulla.
== mRNA Transcript == left|thumb|File:Isoform MSA 2.png|left|thumbleft|thumbMultiple sequence alignment of all C6orf10 human isoforms. This image was generated using Clustal W and M view. C6orf10 contains seven human mRNA splice variants (a, b, c, X1, X2, X3, X4).
Excerpted from Wikipedia’s “TSBP1” article, available under the CC BY-SA 4.0 licence.