TSHB
Sign in to saveAlso known as TSH-B, TSH-BETA, thyroid stimulating hormone beta, Thyroid stimulating hormone, beta, thyroid stimulating hormone subunit beta
Thyroid stimulating hormone, beta also known as TSHB is a protein which in humans is encoded by the TSHB gene.
Gene data
TSHB- Name
- thyroid stimulating hormone subunit beta
- Type
- protein-coding
- Position
- 115,029,826–115,034,302 (+)
- Aliases
- TSH-B, TSH-BETA
- Ensembl
- ENSG00000134200
- RefSeq RNA
- NM_000549.5, NM_001277991.1
- RefSeq protein
- NP_000540.2, NP_001264920.1
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
thyroid stimulating hormone subunit beta
- Symbol
- TSHB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:115,029,826-115,034,302
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 463
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7252
- chromosome
- human chromosome 1
- genomic end
- 115034302
- genomic start
- 115029826
- cytogenetic location
- 1p13.2
- expressed in
- Achilles tendon
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- See also
- References
- Further reading
Thyroid stimulating hormone, beta also known as TSHB is a protein which in humans is encoded by the TSHB gene.
== Function ==
Excerpted from Wikipedia’s “TSHB” article, available under the CC BY-SA 4.0 licence.
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