TWSG1
Sign in to saveAlso known as TSG, twisted gastrulation BMP signaling modulator 1
Twisted gastrulation protein homolog 1 is a protein that in humans is encoded by the TWSG1 gene. The protein is a binding protein for bone morphogenetic proteins, similar to Chordin. The Twisted gastrulation gene is expressed in the extraembryonic tissues during organogenesis, and in certain adult tissues such as the lymph nodes, kidneys, liver, and lungs.
Gene data
TWSG1- Name
- twisted gastrulation BMP signaling modulator 1
- Type
- protein-coding
- Position
- 9,334,618–9,402,424 (+)
- Aliases
- TSG
- Ensembl
- ENSG00000128791
- RefSeq RNA
- NM_020648.6, XM_047437675.1, XM_054318866.1
- RefSeq protein
- NP_065699.1, XP_047293631.1, XP_054174841.1
Enables transforming growth factor beta binding activity. Involved in several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; positive regulation of pathway-restricted SMAD protein phosphorylation; and transforming growth factor beta receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
twisted gastrulation BMP signaling modulator 1
- Symbol
- TWSG1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:9,334,618-9,402,424
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- exact match
- identifiers.org/ncbigene/57045
- HomoloGene ID
- 10774
- found in taxon
- Homo sapiens
- genomic end
- 9402418
- genomic start
- 9334765
- chromosome
- human chromosome 18
- cytogenetic location
- 18p11.22
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Twisted gastrulation protein homolog 1 is a protein that in humans is encoded by the TWSG1 gene. The protein is a binding protein for bone morphogenetic proteins, similar to Chordin. The Twisted gastrulation gene is expressed in the extraembryonic tissues during organogenesis, and in certain adult tissues such as the lymph nodes, kidneys, liver, and lungs.
== References ==
Excerpted from Wikipedia’s “TWSG1” article, available under the CC BY-SA 4.0 licence.