UHMK1
Sign in to saveAlso known as KIS, KIST, P-CIP2, U2AF homology motif (UHM) kinase 1, U2AF homology motif kinase 1
U2AF homology motif (UHM) kinase 1, also known as UHMK1, is a protein which in humans is encoded by the UHMK1 gene.
Gene data
UHMK1- Name
- U2AF homology motif kinase 1
- Type
- protein-coding
- Position
- 162,497,251–162,529,631 (+)
- Aliases
- KIS, KIST, P-CIP2
- Ensembl
- ENSG00000152332
- RefSeq RNA
- NM_001184763.1, NM_144624.2, NM_175866.5
- RefSeq protein
- NP_001171692.1, NP_653225.2, NP_787062.1
The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
U2AF homology motif kinase 1
- Symbol
- UHMK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:162,497,251-162,529,631
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
U2AF homology motif (UHM) kinase 1, also known as UHMK1, is a protein which in humans is encoded by the UHMK1 gene.
==Function==
Excerpted from Wikipedia’s “UHMK1” article, available under the CC BY-SA 4.0 licence.