VAV2

Also known as VAV-2, vav guanine nucleotide exchange factor 2

Guanine nucleotide exchange factor VAV2 is a protein that in humans is encoded by the VAV2 gene.

Gene data

VAV2

Name: vav guanine nucleotide exchange factor 2
Type: protein-coding
Position: 133,761,892–133,992,854 (−)
Aliases: VAV-2
Ensembl: ENSG00000160293
RefSeq RNA: NM_001134398.2, NM_001411028.1, NM_003371.4, XM_017015108.2, XM_017015109.2
RefSeq protein: NP_001127870.1, NP_001397957.1, NP_003362.2, XP_016870597.1, XP_016870598.1

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

Pathways

via MyGene.info

Gene · Ensembl

vav guanine nucleotide exchange factor 2

Symbol: VAV2
Biotype: Protein coding
Organism: Homo sapiens
Location: 9:133,761,892-133,992,854
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein VAV2 PDB 2dlz.png

Show 8 more facts

HomoloGene ID: 2530
genetic association: multiple sclerosis
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/7410
genomic end: 136857726
genomic start: 136627016
chromosome: human chromosome 9
cytogenetic location: 9q34.2

Sources (6)

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Encyclopedic overview

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Guanine nucleotide exchange factor VAV2 is a protein that in humans is encoded by the VAV2 gene.

VAV2 is the second member of the VAV oncogene family. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues.

Excerpted from Wikipedia’s “VAV2” article, available under the CC BY-SA 4.0 licence.