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GeneQ18050514· pop 5· linked from 4 articles

WDR36

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Also known as GLC1G, TA-WDRP, TAWDRP, UTP21, WD repeat domain 36

WD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene.

Gene data

WDR36
Name
WD repeat domain 36
Type
protein-coding
Position
111,092,303–111,130,502 (+)
Aliases
GLC1G, TA-WDRP, TAWDRP, UTP21
Ensembl
ENSG00000134987
RefSeq RNA
NM_139281.3, XM_047416729.1, XM_054351638.1
RefSeq protein
NP_644810.2, XP_047272685.1, XP_054207613.1

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). [provided by RefSeq, Jul 2008].

Gene Ontology

Molecular function

RNA binding

Pathways

Ribosome biogenesis in eukaryotes - Homo sapiens (human)rRNA modification in the nucleus and cytosolMajor pathway of rRNA processing in the nucleolus and cytosolrRNA processingrRNA processingrRNA processing in the nucleus and cytosolrRNA processing in the nucleus and cytosolMetabolism of RNAMetabolism of RNA

via MyGene.info

Gene · Ensembl

WD repeat domain 36

Symbol
WDR36
Biotype
Protein coding
Organism
Homo sapiens
Location
5:111,092,303-111,130,502
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

WD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene.

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).

Excerpted from Wikipedia’s “WDR36” article, available under the CC BY-SA 4.0 licence.

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