WDR5
Sign in to saveAlso known as BIG-3, CFAP89, SWD3, WD repeat-containing protein 5, WD repeat domain 5
WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene.
Gene data
WDR5- Name
- WD repeat domain 5
- Type
- protein-coding
- Aliases
- BIG-3, BIG3, CFAP89, SWD3
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
WD repeat domain 5
- Symbol
- WDR5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:134,134,346-134,159,971
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein WDR5 PDB 2cnx.png
Show 8 more facts
- HomoloGene ID
- 59931
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/11091
- genomic end
- 137025093
- genomic start
- 137000487
- chromosome
- human chromosome 9
- cytogenetic location
- 9q34.2
- expressed in
- gonad
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Excerpted from Wikipedia’s “WDR5” article, available under the CC BY-SA 4.0 licence.