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GeneQ18036115· pop 6· linked from 12 articles

Also known as BIG-3, CFAP89, SWD3, WD repeat-containing protein 5, WD repeat domain 5

WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene.

Gene data

WDR5
Name
WD repeat domain 5
Type
protein-coding
Aliases
BIG-3, BIG3, CFAP89, SWD3

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image
Protein WDR5 PDB 2cnx.png
Show 5 more facts
HomoloGene ID
59931
genomic end
137025093
genomic start
137000487
cytogenetic location
9q34.2
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WD repeat-containing protein 5 is a protein that in humans is encoded by the WDR5 gene.

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

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