WFIKKN2

Also known as GASP-1, WFDC20B, WFIKKNRP, hGASP-1, WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 is a protein that in humans is encoded by the WFIKKN2 gene.

Gene data

WFIKKN2

Name: WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
Type: protein-coding
Position: 50,834,650–50,842,353 (+)
Aliases: GASP-1, WFDC20B, WFIKKNRP, hGASP-1
Ensembl: ENSG00000173714
RefSeq RNA: NM_001330341.2, NM_175575.6
RefSeq protein: NP_001317270.1, NP_783165.1

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway

Molecular function

serine-type endopeptidase inhibitor activity protein binding peptidase inhibitor activity receptor antagonist activity receptor antagonist activity receptor antagonist activity transforming growth factor beta binding transforming growth factor beta binding

Cellular component

extracellular region extracellular region extracellular region

via MyGene.info

Gene · Ensembl

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2

Symbol: WFIKKN2
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:50,834,650-50,842,353
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

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HomoloGene ID: 35284
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/124857
genomic end: 50842353
genomic start: 48912011
chromosome: human chromosome 17
cytogenetic location: 17q21.33

Sources (3)

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Encyclopedic overview

4 sections

Contents

Function
See also
References
Further reading

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 is a protein that in humans is encoded by the WFIKKN2 gene.

== Function ==

Excerpted from Wikipedia’s “WFIKKN2” article, available under the CC BY-SA 4.0 licence.

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