XPO6
Sign in to saveAlso known as EXP6, RANBP20, exportin 6
Exportin-6 is a protein that in humans is encoded by the XPO6 gene.
Gene data
XPO6- Name
- exportin 6
- Type
- protein-coding
- Position
- 28,097,976–28,212,065 (−)
- Aliases
- EXP6, RANBP20
- Ensembl
- ENSG00000169180
- RefSeq RNA
- NM_001270940.2, NM_015171.4
- RefSeq protein
- NP_001257869.1, NP_055986.1
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
exportin 6
- Symbol
- XPO6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:28,097,976-28,212,065
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Exportin-6 is a protein that in humans is encoded by the XPO6 gene.
Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of Ran-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled.
Excerpted from Wikipedia’s “XPO6” article, available under the CC BY-SA 4.0 licence.