ZC3H11A
Sign in to saveAlso known as ZC3HDC11A, zinc finger CCCH-type containing 11A
Zinc finger CCCH domain-containing protein 11A is a protein that in humans is encoded by the ZC3H11A gene. ZC3H11A is a part of the transcription export (TREX) complex and plays a role in exporting of mRNAs from nucleus to cytoplasm. It is considered as stress-induced nuclear protein and maintains mRNAs exporting when the cells are under stress. Loss of functioning of ZC3H11A gene in HeLa cells results in abortion of the replication of nuclear replicating viruses but not cytoplasmic replicating viruses. It is discovered that ZC3H11A is significant for viability and metabolic regulation of mous
Gene data
ZC3H11A- Name
- zinc finger CCCH-type containing 11A
- Type
- protein-coding
- Position
- 203,795,562–203,854,999 (+)
- Aliases
- ZC3HDC11A
- Ensembl
- ENSG00000058673
- RefSeq RNA
- NM_001319238.2, NM_001319239.2, NM_001350261.2, NM_001350262.2, NM_001350263.2
- RefSeq protein
- NP_001306167.1, NP_001306168.1, NP_001337190.1, NP_001337191.1, NP_001337192.1
Enables RNA binding activity. Involved in poly(A)+ mRNA export from nucleus. Colocalizes with transcription export complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
zinc finger CCCH-type containing 11A
- Symbol
- ZC3H11A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:203,795,562-203,854,999
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8888
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9877
- cytogenetic location
- 1q32.1
- genomic end
- 203823252
- chromosome
- human chromosome 1
- genomic start
- 203764782
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Zinc finger CCCH domain-containing protein 11A is a protein that in humans is encoded by the ZC3H11A gene. ZC3H11A is a part of the transcription export (TREX) complex and plays a role in exporting of mRNAs from nucleus to cytoplasm. It is considered as stress-induced nuclear protein and maintains mRNAs exporting when the cells are under stress. Loss of functioning of ZC3H11A gene in HeLa cells results in abortion of the replication of nuclear replicating viruses but not cytoplasmic replicating viruses. It is discovered that ZC3H11A is significant for viability and metabolic regulation of mouse embryo
== References ==
Excerpted from Wikipedia’s “ZC3H11A” article, available under the CC BY-SA 4.0 licence.