ZFP36L1
Sign in to saveAlso known as BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1, ZFP36 ring finger protein-like 1
Butyrate response factor 1 is a protein that in humans is encoded by the ZFP36L1 gene.
Gene data
ZFP36L1- Name
- ZFP36 like 1 zinc finger CCCH-type
- Type
- protein-coding
- Position
- 68,787,655–68,796,269 (−)
- Aliases
- BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1
- Ensembl
- ENSG00000185650
- RefSeq RNA
- NM_001244698.2, NM_001244701.1, NM_004926.4, XM_054376649.1
- RefSeq protein
- NP_001231627.1, NP_001231630.1, NP_004917.2, XP_054232624.1
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ZFP36 ring finger protein like 1
- Symbol
- ZFP36L1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:68,787,655-68,796,269
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ZFP36L1 PDB 1rgo.png
Show 8 more facts
- HomoloGene ID
- 31276
- genetic association
- multiple sclerosis
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/677
- genomic end
- 69263190
- genomic start
- 69254377
- chromosome
- human chromosome 14
- cytogenetic location
- 14q24.1
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Butyrate response factor 1 is a protein that in humans is encoded by the ZFP36L1 gene.
== Function ==
Excerpted from Wikipedia’s “ZFP36L1” article, available under the CC BY-SA 4.0 licence.