ZFP91

Also known as DMS-8, DSM-8, PZF, ZFP-91, ZNF757, FKSG11, ZFP91 zinc finger protein, ZFP91 zinc finger protein, atypical E3 ubiquitin ligase

Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.

Gene data

ZFP91

Name: ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
Type: protein-coding
Aliases: DMS-8, DSM-8, DSM8, FKSG11, PZF, ZFP-91, ZNF757

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010].

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Wikidata facts

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HomoloGene ID: 43144
exact match: identifiers.org/ncbigene/80829
genomic end: 58621550
genomic start: 58579063
cytogenetic location: 11q12.1

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Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. In addition to the monocistronic transcript originating from this locus, a co-transcribed variant composed of ZFP91 and CNTF sequence has been identified. The monocistronic and co-transcribed variants encode distinct isoforms. The co-transcription of ZFP91 and CNTF has also been observed in mouse.