Category
page 11-Naphthyl compounds

propranolol
Propranolol is a medication of the beta blocker class. It is used to treat high blood pressure, some types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, akathisia, performance anxiety, and essential tremors, as well as to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. It can be taken orally, rectally, or by intravenous injection. The formulation that is taken orally comes in short-acting and long-acting versions. Propranolol appears in the blood after 30 minutes and has a maximum effect between 60 and 90 minut

terbinafine
Terbinafine, sold under the brand name Lamisil among others, is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. It is either taken by mouth or applied to the skin as a cream or ointment.

naphazoline
Naphazoline is a medicine used as a decongestant, and a vasoconstrictor added to eye drops to relieve red eye. It has a rapid action in reducing swelling when applied to mucous membranes. It is a sympathomimetic agent with marked alpha adrenergic activity that acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion.
1-naphthol
1-Naphthol, or α-naphthol, is an organic compound with the formula . It is a fluorescent white solid. 1-Naphthol differs from its isomer 2-naphthol by the location of the hydroxyl group on the naphthalene ring. The naphthols are naphthalene homologues of phenol. Both isomers are soluble in simple organic solvents. They are precursors to a variety of useful compounds.
bedaquiline
Bedaquiline, sometimes abbreviated as BDQ and sold under the brand name Sirturo, is a medication used for the treatment of active tuberculosis. Specifically, it is used to treat multi-drug-resistant tuberculosis along with other medications for tuberculosis. It is taken by mouth.
naftifine
Naftifine hydrochloride (brand names include Exoderil and Naftin) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (topical fungal infections).
1-naphthylamine
1-Naphthylamine is an aromatic amine derived from naphthalene. It can cause bladder cancer (transitional cell carcinoma). It crystallizes in colorless needles which melt at 50 °C. It possesses a disagreeable odor, sublimes readily, and turns brown on exposure to air. It is the precursor to a variety of dyes.
1-methylnaphthalene
1-Methylnaphthalene is an organic compound with the formula C11H10. It is a colorless liquid. It is isomeric with 2-methylnaphthalene. It is generally obtained as a minor component of coal tar.
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carbaril
thumb|right|Spraying carbaryl on pine trees
Carbaryl (1-naphthyl methylcarbamate) is an organic compound with the formula . Classified as a carbamate, it is used chiefly as an insecticide. It is a white solid was under the brand name Sevin, which was a trademark of the Bayer Company.
==Production==
Carbaryl is often inexpensively produced by direct reaction of methyl isocyanate with 1-naphthol.
C10H7OH + CH3NCO → C10H7OC(O)NHCH3
1-naphthaleneacetic acid
chemical compound
butenafine
Butenafine, sold under the brand names Lotrimin Ultra, Mentax, and Butop (In India only), is a synthetic benzylamine derived antifungal drug.
1-chloronaphthalene
1-Chloronaphthalene is an aromatic compound. It is a colorless, oily liquid which may be used to determine the refractive index of crystals by immersion. The compound is an isomer to 2-chloronaphthalene.
cinacalcet
Cinacalcet, sold under the brand name Sensipar among others, is a medication used to treat primary hyperparathyroidism, tertiary hyperparathyroidism and parathyroid carcinoma. Cinacalcet acts as a calcimimetic (i.e., it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues.
Ponceau 6R
chemical compound
ANTU
nafronyl
Naftidrofuryl, also known as nafronyl and sold under the brand name Praxilene among others, is a serotonin 5-HT2 receptor antagonist which is used as a vasodilator in the treatment of peripheral and cerebral vascular disorders. It is taken orally.
1-nitronaphthalene
1-Nitronaphthalene is an organic compound with the formula . It is one of two isomers of nitronaphthalene. A pale yellow, sublimable solid, 1-nitronaphthalene is the main product of the direct nitration of naphthalene. It is an intermediate in the production of naphthylamine, a precursor to dyes. The conversion to the amine is effected by hydrogenation.
1-bromonaphthalene
1-Bromonaphthalene is an organic compound with the formula C10H7Br. thumb|1-Bromonaphthalene It is one of two isomeric bromonaphthalenes, the other being 2-bromonaphthalene. Under normal conditions, the substance is a colorless liquid.
naphthaleneacetamide
1-Naphthaleneacetamide (NAAm) is a synthetic auxin that acts as a rooting hormone. NAAm is potentially genotoxic and cytotoxic on human peripheral blood lymphocytes in vitro.
1-fluoronaphthalene
1-Fluornaphthalene is an organofluorine chemical compound from the group of naphthalene derivatives and fluoroaromatics. Its chemical formula is .
1-naphthyl isothiocyanate
chemical compound
tideglusib
Tideglusib (NP-12, NP031112) is a potent and irreversible small molecule glycogen synthase kinase 3 (GSK-3) inhibitor.
N-phenyl-1-naphthylamine
'''N-Phenylnaphthalen-1-amine (NPN''') is an aromatic amine with the chemical formula .
bunaftine
Bunaftine (or bunaphtine) is an antiarrhythmic agent. It is classified in class III.
1-naphthalenesulfonic acid
chemical compound
naphthylvinylpyridine
Naphthylvinylpyridine (NVP) is a naphthalene derivative that possesses anticholinergic activity similar to that of atropine. However, NVP's method of acetylcholine (ACh) antagonism involves inhibiting the enzyme choline acetyltransferase.
cerlapirdine
Cerlapirdine (USAN; SAM-531, WAY-262,531, PF-05212365) is a drug which was under development by Wyeth/Pfizer for the treatment of cognitive disorders associated with Alzheimer's disease and schizophrenia. In a phase II clinical trial it demonstrated a trend toward efficacy along with a good side effect profile and no incidence of serious adverse events, but no further development has occurred since 2011.
AOH1996
AOH1996 is an experimental anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for the treatment of solid tumors.
1-naphthalenethiol
1-Naphthalenethiol is an organosulfur compound with the formula C10H7SH. It is a white solid. It is one of two monothiols of naphthalene, the other being 2-naphthalenethiol.
N,N-dimethyl-1-naphthylamine
'''N,N-Dimethyl-1-naphthylamine' is an aromatic amine. It is formally derived from 1-naphthylamine by replacing the hydrogen atoms on the amino group with methyl groups. N,N''-Dimethyl-1-naphthylamine is used in the nitrate reductase test to form a precipitate of a red azo dye by reacting with a nitrite-sulfanilic acid complex.
1-naphthoic acid
chemical compound
nadoxolol
Nadoxolol is an antiarrhythmic agent (i.e., a drug for the treatment of irregular heartbeat), chemically related in structure to beta-adrenergic receptor blocker drugs such as propranolol.