Skip to content
Category

Benzopyrans

page 1
novobiocin
Novobiocin, also known as albamycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which is a heterotypic synonym for S. spheroides a member of the class Actinomycetia. Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. Novobiocin was first reported in the mid-1950s (then called streptonivicin).
cannabichromene
Cannabichromene (CBC), also called cannabichrome, cannanbichromene, pentylcannabichromene or cannabinochromene, is a phytocannabinoid, one of the hundreds of cannabinoids found in the Cannabis plant. It bears structural similarity to the other natural cannabinoids, including tetrahydrocannabinol (THC), tetrahydrocannabivarin (THCV), cannabidiol (CBD), and cannabinol (CBN), among others. It is not scheduled by the Convention on Psychotropic Substances.
iclaprim
Iclaprim is an antibiotic drug candidate that is active against Gram positive organisms. It is administered intravenously.
tocofersolan
Tocofersolan (INN; also known as tocophersolan, tocopherol polyethylene glycol succinate, or TPGS) is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is a polyethylene glycol (PEG) derivative of α-tocopherol succinate. The addition of PEG enables water solubility.
YCT529
YCT529 is an experimental non-hormonal male contraceptive developed by YourChoice Therapeutics. It functions as a selective antagonist of the retinoic acid receptor alpha (RAR-α), a nuclear receptor involved in vitamin A signaling. By inhibiting RAR-α, YCT529 disrupts spermatogenesis, leading to temporary infertility. YCT529 targets RAR-α, which plays a crucial role in the vitamin A signaling pathway essential for sperm production. By selectively inhibiting RAR-α, the drug impedes the development and maturation of sperm cells without affecting other physiological processes governed by vitamin
cannabicyclol
Cannabicyclol (CBL) is a non-psychoactive cannabinoid found in Cannabis. CBL is a degradative product like cannabinol, with cannabichromene degrading into CBL through natural irradiation or under acid conditions.
(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-[1]benzopyrano[4,3-b][1,4]oxazin-9-ol
PD-128,907 is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D2 and D3 receptors. It is used for studying the role of these receptors in the brain, in roles such as inhibitory autoreceptors that act to limit further dopamine release, as well as release of other neurotransmitters. In animal studies, it has been shown to reduce toxicity from cocaine overdose.
alniditan
Alniditan (, ; developmental code name R-91274) is a selective serotonin 5-HT1B and 5-HT1D receptor agonist with migraine-preventive effects which was never marketed. It was under development for treatment of migraine via subcutaneous injection in the 1990s and reached phase 3 clinical trials for this indication prior to the discontinuation of its development.
SPANphos
SPANphos is an organophosphorus compound used as a ligand in organometallic and coordination chemistry. The compound is a rare example of a trans-spanning ligand and rigidly links mutually trans coordination sites. By virtue of its C2-symmetric backbone, SPANphos forms a chiral cavity over the face of a square planar complexes, e.g. in MCl2(SPANphos) (M = Pd, Pt).thumb|left|144px|Structure of PtCl2(SPANphos)
Menabitan
Menabitan (INN: SP-204) is a synthetic drug which acts as a potent cannabinoid receptor agonist. It is closely related to natural cannabinoids of the tetrahydrocannabinol (THC) group, differing mainly by its longer and branched side chain, and the replacement of the 9-position carbon with a nitrogen. It is a structural analog of nabitan and dimethylheptylpyran. It was studied as an analgesic in the 1970s and was found to possess analgesic effects in both humans and animals but was never marketed.
nabitan
Nabitan (nabutam, benzopyranoperidine, SP-106, Abbott 40656) is a synthetic cannabinoid analog of dronabinol (Δ9-tetrahydrocannabinol) and dimethylheptylpyran. It exhibits antiemetic and analgesic effects, most likely by binding to and activating the CB1 and CB2 cannabinoid receptors, and reduced intraocular pressure in animal tests, making it potentially useful in the treatment of glaucoma.