novobiocin
Novobiocin, also known as albamycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which is a heterotypic synonym for S. spheroides a member of the class Actinomycetia. Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. Novobiocin was first reported in the mid-1950s (then called streptonivicin).
Research
3,600 papers- Novobiocin Analogs as Potential Anticancer Agents.Mini reviews in medicinal chemistry · 2017
- Novobiocin.Progress in industrial microbiology · 1961
- Vancomycin and novobiocin.The Medical clinics of North America · 1970
- NOVOBIOCIN.Quarterly review of pediatrics · 1956
- [Novobiocin].Il Farmaco; edizione scientifica · 1956
via PubMed
Article
7 sectionsContents
- Clinical use
- Mechanism of action
- Structure
- Structure–activity relationship
- Biosynthesis
- References
- External links
Novobiocin, also known as albamycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which is a heterotypic synonym for S. spheroides a member of the class Actinomycetia. Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. Novobiocin was first reported in the mid-1950s (then called streptonivicin).
==Clinical use== It is active against Staphylococcus epidermidis and may be used to differentiate S. epidermidis from coagulase-negative Staphylococcus saprophyticus, which is resistant to novobiocin, in culture.