iclaprim
Sign in to saveIclaprim is an antibiotic drug candidate that is active against Gram positive organisms. It is administered intravenously.
Chemical data
- Formula
- C19H22N4O3
- Molecular weight
- 354.4 g/mol
- IUPAC name
- 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine
via PubChem
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Iclaprim is an antibiotic drug candidate that is active against Gram positive organisms. It is administered intravenously.
In vitro, iclaprim is active against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Staphylococcus aureus (VRSA), strains of Streptococcus pneumoniae resistant to several common antibiotics, and some Gram-negative bacteria. It is of the diaminopyrimidine dihydrofolate reductase (DHFR)-inhibiting type.
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AminopyrimidinesBacterial dihydrofolate reductase inhibitorsBenzopyransChemical pages without DrugBank identifierCyclopropyl compoundsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs with non-standard legal statusECHA InfoCard ID from WikidataExperimental drugsPhenol ethers