Category
page 1Chloride channels
cystic fibrosis transmembrane conductance regulator
mammalian protein found in Homo sapiens

chloride channel
class of transport proteins
CLCN1
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen).
CLCA2
Chloride channel accessory 2 is a protein that in humans is encoded by the CLCA2 gene.
CLCA1
Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.
ANO1
Anoctamin-1 (ANO1), also known as Transmembrane member 16A (TMEM16A), is a protein that, in humans, is encoded by the ANO1 gene. Anoctamin-1 is a voltage-gated calcium-activated anion channel, which acts as a chloride channel and a bicarbonate channel. additionally Anoctamin-1 is apical iodide channel.