CLCA1
Sign in to saveAlso known as CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1, chloride channel accessory 1
Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.
In the Vinony graph
Within Vinony's link graph, CLCA1 is referenced by 302 other articles, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
Vinony files it under Chloride channels and Genes on human chromosome 1.
Its subject is documented across 4 Wikipedia language editions.
Gene data
CLCA1- Name
- chloride channel accessory 1
- Type
- protein-coding
- Position
- 86,468,368–86,501,401 (+)
- Aliases
- CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1
- Ensembl
- ENSG00000016490
- RefSeq RNA
- NM_001285.4
- RefSeq protein
- NP_001276.3
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
chloride channel accessory 1
- Symbol
- CLCA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:86,468,368-86,501,401
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 984
- genomic start
- 86468368
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1179
- genomic end
- 86500259
- chromosome
- human chromosome 1
- cytogenetic location
- 1p22.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- See also
- References
- Further reading
- External links
Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. Protein structure prediction methods suggest the N-terminal region of CLCA1 protein is a zinc metalloprotease.
Excerpted from Wikipedia’s “CLCA1” article, available under the CC BY-SA 4.0 licence.