Co-chaperones

BAG family molecular chaperone regulator 4 is a protein that in humans is encoded by the BAG4 gene.

Heat shock 10 kDa protein 1 (Hsp10), also known as chaperonin 10 (cpn10) or early-pregnancy factor (EPF), is a protein that in humans is encoded by the HSPE1 gene. The homolog in E. coli is GroES that is a chaperonin which usually works in conjunction with GroEL.

protein-coding gene in the species Homo sapiens

Sacsin also known as DnaJ homolog subfamily C member 29 (DNAJC29) is a protein that in humans is encoded by the SACS gene. Sacsin is a Hsp70 co-chaperone.

protein-coding gene in the species Homo sapiens

Protein unc-45 homolog A is a protein that in humans is encoded by the UNC45A gene.

BAG family molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy.

FK506-binding protein 4 is a protein that in humans is encoded by the FKBP4 gene.

Mitochondrial import receptor subunit TOM70, also known as translocase of outer mitochondrial membrane protein 70 is a protein that in humans is encoded by the TOMM70 gene.

Putative tyrosine-protein phosphatase auxilin is an enzyme that in humans is encoded by the DNAJC6 gene.

FK506-binding protein like, also known as FKBPL, is a protein that in humans is encoded by the FKBPL gene.

BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.

Mitochondrial import receptor subunit TOM34 is a protein that in humans is encoded by the TOMM34 gene.

Small glutamine-rich tetratricopeptide repeat-containing protein alpha is a protein that in humans is encoded by the SGTA gene. SGTA orthologs have also been identified in several mammals for which complete genome data are available. STGA belongs to a family of co-chaperone proteins that obtain a TPR motif. STGA was discovered just 15 years ago.

Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a HSP90 Co-chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.