BAG1
Sign in to saveAlso known as BAG-1, HAP, RAP46, BCL2 associated athanogene 1, BAG cochaperone 1
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.
Gene data
BAG1- Name
- BAG cochaperone 1
- Type
- protein-coding
- Position
- 33,247,820–33,264,720 (−)
- Aliases
- BAG-1, HAP, RAP46
- Ensembl
- ENSG00000107262
- RefSeq RNA
- NM_001172415.2, NM_001349286.2, NM_001349299.2, NM_004323.6
- RefSeq protein
- NP_001165886.1, NP_001336215.1, NP_001336228.1, NP_004314.6
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
BAG cochaperone 1
- Symbol
- BAG1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:33,247,820-33,264,720
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
6 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- External links
- Further reading
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.
== Function ==
Excerpted from Wikipedia’s “BAG1” article, available under the CC BY-SA 4.0 licence.