Diols

Fenpentadiol (INN; brand names Tredum, Trefenum; developmental code Rd-292; also known as phenpentanediol) is a drug described as a tranquilizer and antidepressant that was formerly marketed in Europe. It also has stimulant, sedative, and anxiolytic effects, with the latter two occurring only at higher doses.

chemical compound

'''cis-Butene-1,4-diol''' is a chemical compound used in the production of endosulfan. It reacts with hexachlorocyclopentadiene to form endosulfan diol. Endosulfan diol then reacts with thionyl chloride to form endosulfan.

HU-243 (AM-4056) is a synthetic cannabinoid drug that is a single enantiomer of the hydrogenated derivative of the commonly used reference agonist HU-210. It is a methylene homologue of canbisol. It is a potent agonist at both the CB1 and CB2 receptors, with a binding affinity of 0.041 nM at the CB1 receptor, making it marginally more potent than HU-210, which had an affinity of 0.061 nM in the same assay.

Pectolinarigenin is a Cirsium isolate with anti-inflammatory activity and belongs to the flavones.

chemical compound

chemical compound

Hawkinsin (also known as 2-cystenyl-1,4-dihydroxycyclohexenylacetate) is an amino acid, which is formed after detoxification of a reactive tyrosine metabolite (quinol acetate) by glutathione. Hawkinsin is ninhydrin positive (a common test to detect amino acids and proteins with a free -NH2 group).

Iodoresiniferatoxin (I-RTX) is a strong competitive antagonist of the Transient Receptor Potential Vanilloid 1 (TRPV1) receptor. I-RTX is derived from resiniferatoxin (RTX).

chemical compound

Dimethylsilanediol or DMSD is an organosilicon compound with the chemical formula . It is a colorless crystalline solid. It belongs to the category of silanols. Molecule of dimethylsilanediol has tetrahedral molecular geometry, where two methyl and two hydroxyl groups are attached to the central silicon atom. Dimethylsilanediol is a silicon analog of unstable propane-2,2-diol , where the central C atom is replaced by Si atom.

chemical compound

Serinol is the organic compound with the formula . A colorless solid, it is classified both as an amino alcohol and as a diol. It is structurally related to glycerol. Its name reflects the compound's relationship to the amino acid serine, from which it can be produced by hydrogenation. Other amino alcohols derived from amino acids: alaninol, leucinol, tyrosinol.

Daigremontianin is a bufadienolide. Bufadienolides are steroids and cardiac glycoside aglycones (meaning that they bind with carbohydrates to form cardiac glycosides) that are similar to cardenolides, differing only in the structure of the C-17 substituent on the D ring. This chemical has been found to be toxic in experiments on mice. It is one of five bufadienolides that have been isolated from Kalanchoe daigremontiana.

Oxabolone is a synthetic anabolic-androgenic steroid (AAS) of the nandrolone (19-nortestosterone) group which was never marketed. It can be formulated as the cipionate ester prodrug oxabolone cipionate, which, in contrast, has been marketed for medical use.

'''N,N-Dimethylsphingosine (also known as DMS''') is an inhibitor of sphingosine kinase.

mixture of chemical compounds

Nifurquinazol (NF-1088) is an antibacterial agent of the nitrofuran class. It was never marketed. ==Synthesis== thumb|center|700px|Nifurquinazol synthesis: Treatment of the amide from 5-nitrofuroic acid with phosphorus oxychloride leads to the corresponding nitrile (2). This intermediate is then converted to the iminoether (3) with ethanolic hydrogen chloride. Condensation of anthranilic acid with the iminoether in the presence of sodium methoxide represents another method for preparing quinazolones. The reaction can be visualized as proceeding through the formation of the amidine from additio