Daigremontianin is a bufadienolide. Bufadienolides are steroids and cardiac glycoside aglycones (meaning that they bind with carbohydrates to form cardiac glycosides) that are similar to cardenolides, differing only in the structure of the C-17 substituent on the D ring. This chemical has been found to be toxic in experiments on mice. It is one of five bufadienolides that have been isolated from Kalanchoe daigremontiana.
Daigremontianin is a bufadienolide. Bufadienolides are steroids and cardiac glycoside aglycones (meaning that they bind with carbohydrates to form cardiac glycosides) that are similar to cardenolides, differing only in the structure of the C-17 substituent on the D ring. This chemical has been found to be toxic in experiments on mice. It is one of five bufadienolides that have been isolated from Kalanchoe daigremontiana.
==Toxicity== Daigremontianin causes potentially fatal cardiac arrhythmias, but repeated sub-lethal doses cause a condition called cotyledonosis, an intoxication affecting nervous and muscular systems of small animals, particularly, sheep in the Karoo area of South Africa.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).