Category

EC 2.1.1

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catechol-O-methyltransferase

thumb|350px|Norepinephrine degradation. Catechol-O-methyltransferase is shown in green boxes. 'Catechol-O-methyltransferase (COMT'; ) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure. In humans, catechol-O-methyltransferase protein is encoded by the COMT gene. Two isoforms of COMT are produced: the soluble short form (S-COMT) and the membrane bound long form (MB-COMT). As the regulation of catecholamines is impaired in a number of medical c

5-methyltetrahydrofolate-homocysteine methyltransferase

mammalian protein found in Homo sapiens

Phenylethanolamine N-methyltransferase

mammalian protein found in Homo sapiens

DNA methyltransferase

class of enzymes

histone methyltransferase

class of enzymes

methyltransferase

thumb|300x300px|SET7/9, a representative histone methyltransferase with SAM (blue) and peptide undergoing methylation (black). Rendered from PDB: 4J83. thumb|320px|The SN2-like methyl transfer reaction. Only the SAM cofactor and cytosine base are shown for simplicity.

Thymidylate synthetase

mammalian protein found in Homo sapiens

Thiopurine S-methyltransferase

mammalian protein found in Homo sapiens

Guanidinoacetate N-methyltransferase

mammalian protein found in Homo sapiens

histamine N-methyltransferase

mammalian protein found in Homo sapiens

Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by gene, that participates in histone methylation and, ultimately, transcriptional repression. EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-methionine. Methylation activity of EZH2 facilitates heterochromatin formation thereby silences gene function. Remodeling of chromosomal heterochromatin by EZH2 is also required during cell mitosis.

RNA guanine-7 methyltransferase

mammalian protein found in Homo sapiens

betaine-homocysteine S-methyltransferase

class of enzymes

Site-specific DNA-methyltransferase (adenine-specific)

Glycine N-methyltransferase

class of enzymes

Amine N-methyltransferase

class of enzymes

Caffeate O-methyltransferase

class of enzymes

protein-coding gene in the species Homo sapiens

Euchromatic histone-lysine N-methyltransferase 1, also known as G9a-like protein (GLP), is a protein that in humans is encoded by the EHMT1 gene.

Isoorientin 3'-O-methyltransferase

class of enzymes

Flavin-dependent thymidylate synthase

class of enzymes

Homocysteine S-methyltransferase

class of enzymes

Methionine S-methyltransferase

class of enzymes

Tryptophan 2-C-methyltransferase

class of enzymes

Tocopherol O-methyltransferase

class of enzymes

protein-L-isoaspartate (D-aspartate) O-methyltransferase

class of enzymes

3,7-dimethylquercetin 4'-O-methyltransferase

class of enzymes

Quercetin 3-O-methyltransferase

class of enzymes

trans-aconitate 2-methyltransferase

class of enzymes

Inositol 1-methyltransferase

class of enzymes

Sterol 24-C-methyltransferase

class of enzymes

Putrescine N-methyltransferase

class of enzymes

Macrocin O-methyltransferase

class of enzymes

Isoliquiritigenin 2'-O-methyltransferase

class of enzymes

tRNA (cytosine-5-)-methyltransferase

class of enzymes

Isoflavone 4'-O-methyltransferase

class of enzymes

Thiol S-methyltransferase

class of enzymes

Chlorophenol O-methyltransferase

class of enzymes

Anthranilate N-methyltransferase

class of enzymes

Phosphoethanolamine N-methyltransferase

class of enzymes

Tetrahydrocolumbamine 2-O-methyltransferase

class of enzymes

calmodulin-lysine N-methyltransferase

class of enzymes

Inositol 3-methyltransferase

class of enzymes

8-hydroxyfuranocoumarin 8-O-methyltransferase

class of enzymes

Tetrahydromethanopterin S-methyltransferase

class of enzymes

Hexaprenyldihydroxybenzoate methyltransferase

class of enzymes

Fatty-acid O-methyltransferase

class of enzymes

Magnesium protoporphyrin IX methyltransferase

class of enzymes

Deoxycytidylate C-methyltransferase

class of enzymes

8-hydroxyquercetin 8-O-methyltransferase

class of enzymes

pyridine N-methyltransferase

class of enzymes

Polysaccharide O-methyltransferase

class of enzymes

Protein-glutamate O-methyltransferase

class of enzymes

Trimethylsulfonium-tetrahydrofolate N-methyltransferase

class of enzymes

Kaempferol 4'-O-methyltransferase

class of enzymes

Isobutyraldoxime O-methyltransferase

class of enzymes

Jasmonate O-methyltransferase

class of enzymes

Licodione 2'-O-methyltransferase

class of enzymes

Phenol O-methyltransferase

class of enzymes

3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase

class of enzymes