EHMT1

Name

euchromatic histone lysine methyltransferase 1

Type

protein-coding

Position

137,618,977–137,870,016 (+)

Aliases

EHMT1-IT1, EUHMTASE1, Eu-HMTase1, FP13812, GLP, GLP1, KLEFS1, KMT1D

Ensembl

ENSG00000181090

RefSeq RNA

NM_001039765.1, NM_001145527.2, NM_001354259.2, NM_001354263.2, NM_001354611.2

RefSeq protein

NP_001138999.1, NP_001341188.1, NP_001341192.1, NP_001341540.1, NP_001341541.1

The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017].

via MyGene.info

Gene · Ensembl

euchromatic histone lysine methyltransferase 1

Symbol

EHMT1

Biotype

Protein coding

Organism

Homo sapiens

Location

9:137,618,901-137,870,016

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0