EC 4.2.1

class of enzymes

Fumarase (or fumarate hydratase) is an enzyme () that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs cycle and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.

class of enzymes

mammalian protein found in Homo sapiens

class of enzymes

mammalian protein found in Homo sapiens

thumb|Imidazol-4-one-5-propionic acid

protein-coding gene in the species Homo sapiens

class of enzymes

class of enzymes

class of enzymes

Aconitase 1, soluble is a protein that in humans is encoded by the ACO1 gene.

class of enzymes

protein family

protein-coding gene in the species Homo sapiens

class of enzymes