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Aconitase
EntityQ342083· pop 25· linked from 505 articles

Also known as cis-aconitase, citrate(isocitrate) hydro-lyase, citrate(isocitrate) hydro-lyase (cis-aconitate-forming)

Key facts

Enzyme.CAS_number
9024-25-3
Enzyme.Name
aconitate hydratase
Enzyme.EC_number
4.2.1.3
Enzyme.GO_code
0003994
Enzyme.image
7ACN.jpg
Enzyme.caption
Illustration of pig aconitase in complex with the [Fe4S4] cluster. The protein is colored by secondary structure, and iron atoms are blue and the sulfur red.
Protein family.Symbol
Aconitase
Protein family.Name
Aconitase family(aconitate hydratase)
Protein family.image
PDB 1aco EBI.jpg
Protein family.caption
Structure of aconitase.
Protein family.Pfam
PF00330
Protein family.InterPro
IPR001030
Protein family.PROSITE
PDOC00423
Protein family.SCOP
1aco
Protein.Name
aconitase 2, mitochondrial
Protein.HGNCid
118
Protein.Symbol
ACO2
Protein.AltSymbols
ACONM

via Wikipedia infobox

~6 min read

Encyclopedic overview

8 sections
Contents
  • Structure
  • Function
  • Mechanism
  • Family members
  • Interactive pathway map
  • References
  • Further reading
  • External links

Aconitase (aconitate hydratase; ) is an enzyme that catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle, a non-redox-active process.

Image:Citrate wpmp.png| Image:Aconitic acid.svg| Image:isocitric acid.svg|

Excerpted from Wikipedia’s “Aconitase” article, available under the CC BY-SA 4.0 licence.

Gallery (6)