Histopathology

lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in liver cells via the process of steatosis

subtype of basal-cell carcinoma most commonly occurring on the sun-exposed areas of the head and neck

thumb|Normal squamous cells thumb|Dysplastic cells Dysplasia is any of various types of abnormal growth or development of cells (microscopic scale) or organs (macroscopic scale), and the abnormal histology or anatomical structure(s) resulting from such growth. Dysplasias on a mainly microscopic scale include epithelial dysplasia and fibrous dysplasia of bone. Dysplasias on a mainly macroscopic scale include hip dysplasia, myelodysplastic syndrome, and multicystic dysplastic kidney.

histological stain method using hematoxylin and eosin

thumb|right|350px|Micrograph|Microscope image showing [[contraction band necrosis, a histopathologic finding of myocardial infarction (heart attack).]] Histopathology (compound of three Greek words: 'tissue', 'suffering', and -logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides. In contrast, cytopathology examines f

Metaplasia () is the transformation of a cell type to another cell type. The change from one type of cell to another may be part of a normal maturation process, or caused by some sort of abnormal stimulus. In simplistic terms, it is as if the original cells are not robust enough to withstand their environment, so they transform into another cell type better suited to their environment. If the stimulus causing metaplasia is removed or ceases, tissues return to their normal pattern of differentiation. Metaplasia is not synonymous with dysplasia, and is not considered to be an actual cancer. It i

A papilloma (plural papillomas or papillomata) (papillo- + -oma) is a benign epithelial tumor growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context, papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple).

microbiological method for identification

stain used for diagnosis of malaria

thumb|upright=1.2|Density-Dependent Colour Scanning Electron Micrograph SEM (DDC-SEM) of cardiovascular calcification, showing in orange calcium phosphate spherical particles (denser material) and, in green, the extracellular matrix (less dense material).

thumb|Micrograph showing amyloid deposits (pink) in [[small bowel. Duodenum with amyloid deposition in lamina propria. Amyloid shows up as homogeneous pink material in lamina propria and around blood vessels. 20× magnification. ]] Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β) and ability to be stained by particular dyes, such as Congo red. In the human body, amyloids have been linked to the development of various diseases. Pathogenic amyloids form when previously healthy proteins lo

human disease

thumb|Osteopenia exists on a spectrum of normal to dangerously low bone density (osteoporosis).

chemical compound

thumb|Acanthocytes, from peripheral blood, under light microscopy. Note the irregularly shaped, non-circular cells in the image.

slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal columns (posterior columns) of the spinal cord (the portion closest to the back of the body) and dorsal roots

in microbiology

tertiary syphilis that is characterized by granulomatous lesions, called gummas, which are characterized by a center of necrotic tissue with a rubbery texture. They form in the liver, bones, and testes but may affect any organ

form of cell death

cell type associated with Hodgkin lymphoma

Tauopathies are a class of heterogeneous neurodegenerative diseases characterized by the neuronal and glial aggregation of abnormal tau protein. Hyperphosphorylation of tau proteins causes them to dissociate from microtubules and form insoluble aggregates called neurofibrillary tangles. Various neuropathologic phenotypes have been described based on the anatomical regions and cell types involved as well as the unique tau isoforms making up these deposits. The designation 'primary tauopathy' is assigned to disorders where the predominant feature is the deposition of tau protein. Alternatively,

Human disease

extracellular deposit of amyloid beta in the grey matter of the brain

Steatosis, also called fatty change, is abnormal retention of fat (lipids) within a cell or organ. Steatosis most often affects the liver – the primary organ of lipid metabolism – where the condition is commonly referred to as fatty liver disease. Steatosis can also occur in other organs, including the kidneys, heart, and muscle. When the term is not further specified (as, for example, in 'cardiac steatosis'), it is assumed to refer to the liver.

rare disease

large, crystalline cytoplasmic inclusion bodies sometimes observed in myeloid blast cells

cytoplasmic hyaline inclusions in a hepatocyte

nodule found in the heart of an individual with rheumatic fever

Microangiopathy (also known as microvascular disease, small vessel disease (SVD) or microvascular dysfunction) is a disease of the microvessels, small blood vessels in the microcirculation. It can be contrasted to macroangiopathies such as atherosclerosis, where large and medium-sized arteries (e.g., aorta, carotid and coronary arteries) are primarily affected.

irreversible, uncontrolled cell death

lung cancer that derives from the distal bronchioles or alveoli that initially exhibit a specific non-invasive growth pattern

SACD

A hyaline substance is one with a glassy appearance. The word is derived from , and .

pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury

embryonal cancer that is a type of germ cell tumour, located in the ovaries or testes

thumb|Scanning electron microscopy (SEM) of echinocytes thumb|Echinocyte compared to other forms of poikilocytosis Echinocyte (from the Greek word echinos, meaning 'hedgehog' or 'sea urchin'), in human biology and medicine, refers to a form of red blood cell that has an abnormal cell membrane characterized by many small, evenly spaced thorny projections. A more common term for these cells is burr cells.

medical test

group of medical specialties

Feature of Tuberculosis seen in Chest X-Ray

ectopic calcification

human disease

cellular inclusion body

chemical compound

histological staining method

idiopathic interstitial pneumonia that is characterized by the accumulation of bronchiolocentric alveolar macrophages in alveolar spaces and interstitial inflammation and involves mild bronchiolar fibrosis and chronic inflammation

human disease

basophilic leukocyte inclusions located in the peripheral cytoplasm of neutrophils

medical condition

variant of polyarthritis

microscopic finding in the sputum of asthmatics

field staining

cell with a large vacuole

pathognomic of Granulosa cell tumor ovary (Sex Cord Tumor)

medical diagnostic method

Type of granules

fnding in interstitial lung disease suggestive of significant asbestos exposure

benign transformation of surface lining cells to a squamous morphology