histopathology
Sign in to savethumb|right|350px|Micrograph|Microscope image showing [[contraction band necrosis, a histopathologic finding of myocardial infarction (heart attack).]] Histopathology (compound of three Greek words: 'tissue', 'suffering', and -logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides. In contrast, cytopathology examines f
Article
12 sectionsContents
- Collection of tissues
- Preparation for histology
- Chemical fixation
- Processing
- Frozen section processing
- Staining of processed histology slides
- Interpretation
- Architectural patterns
- Nuclear patterns
- See also
- References
- External links
thumb|right|350px|Micrograph|Microscope image showing [[contraction band necrosis, a histopathologic finding of myocardial infarction (heart attack).]] Histopathology (compound of three Greek words: 'tissue', 'suffering', and -logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides. In contrast, cytopathology examines free cells or tissue micro-fragments (as "cell blocks").
== Collection of tissues == Histopathological examination of tissues starts with surgery, biopsy, or autopsy. The tissue is removed from the body or plant, and then, often following expert dissection in the fresh state, placed in a fixative which stabilizes the tissues to prevent decay. The most common fixative is 10% neutral buffered formalin (corresponding to 3.7% w/v formaldehyde in neutral buffered water, such as phosphate buffered saline).