steatosis
Sign in to saveAlso known as fatty change
Steatosis, also called fatty change, is abnormal retention of fat (lipids) within a cell or organ. Steatosis most often affects the liver – the primary organ of lipid metabolism – where the condition is commonly referred to as fatty liver disease. Steatosis can also occur in other organs, including the kidneys, heart, and muscle. When the term is not further specified (as, for example, in 'cardiac steatosis'), it is assumed to refer to the liver.
Key facts
- Medical condition (new).name
- Steatosis
- Medical condition (new).synonyms
- Fatty change, fatty degeneration, fatty atrophy, adipose degeneration, fatty infiltration, fatty replacement
- Medical condition (new).image
- Non-alcoholic fatty liver disease1.jpg
- Medical condition (new).caption
- Micrograph demonstrating marked (macrovesicular) steatosis in metabolic dysfunction–associated steatotic liver disease. Masson's trichrome stain.
- Medical condition (new).field
- Gastroenterology
- Medical condition (new).complications
- Fatty liver disease
via Wikipedia infobox
Health references
- ICD-10
- E88.810 — Metabolic syndrome
Clinical Trials
2,134 registered- NACOMPLETEDInfluence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters.Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis · NCT06275906
- NACOMPLETEDDiabetes Prevention Program for the Treatment of Nonalcoholic Fatty Liver DiseaseIcahn School of Medicine at Mount Sinai · NCT04988204
- NACOMPLETEDThe Efficacy of S-adenosyl Methionine (SAMe) Versus Pentoxiphylline in Patients With Non-alcoholic Steatohepatitis With FibrosisInstitute of Liver and Biliary Sciences, India · NCT02231333
- NOT_YET_RECRUITINGAn Observational Clinical Study on the Association of Intestinal Ruminococcus Gnavus and Its Derived Biogenic Amines With Metabolic Dysfunction-associated Fatty Liver DiseaseZhujiang Hospital · NCT07455149
- PHASE2UNKNOWNSafety, Tolerability, and Efficacy of AXA1125 in NASH With FibrosisAxcella Health, Inc · NCT04880187
- PHASE4COMPLETEDAntidiabetic Drugs for Steatotic Liver DiseaseYonsei University · NCT03646292
~9 min read
Encyclopedic overview
9 sectionsContents
- Pathogenesis
- Macrovesicular steatosis
- Microvesicular steatosis
- Histology
- Medical imaging
- Incidence
- See also
- References
- External links
Steatosis, also called fatty change, is abnormal retention of fat (lipids) within a cell or organ. Steatosis most often affects the liver – the primary organ of lipid metabolism – where the condition is commonly referred to as fatty liver disease. Steatosis can also occur in other organs, including the kidneys, heart, and muscle. When the term is not further specified (as, for example, in 'cardiac steatosis'), it is assumed to refer to the liver.
Risk factors associated with steatosis are varied, and may include diabetes mellitus, protein malnutrition, hypertension, cell toxins, obesity, anoxia, and sleep apnea.
Excerpted from Wikipedia’s “steatosis” article, available under the CC BY-SA 4.0 licence.