Para-Phenylene compounds

Fexofenadine, sold under the brand name Allegra among others, is an antihistamine medication used in the treatment of allergy symptoms such as allergic rhinitis and urticaria.

Colestyramine (INN) or cholestyramine (USAN) (trade names Questran, Questran Light, Cholybar, Olestyr, Quantalan, Vasosan) is a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption. It is a strong ion exchange resin, which means it can exchange its chloride anions with anionic bile acids in the gastrointestinal tract and bind them strongly in the resin matrix. The functional group of the anion exchange resin is a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer.

POPOP or 1,4-bis(5-phenyloxazol-2-yl) benzene is a scintillator. It is used as a wavelength shifter (also called a "secondary scintillator"), which means that it converts shorter wavelength light to longer wavelength light. Its output spectrum peaks at 410 nm, which is violet. POPOP is used in both solid and liquid organic scintillators.

thumb|right|200px|The structure of the repeating unit of PPP thumb|right|200px|Space-filling model of a short section of PPP 'Poly(p-phenylene) (PPP') is made of repeating p-phenylene units, which act as the precursor to a conducting polymer of the rigid-rod polymer family. The synthesis of PPP has proven challenging, but has been accomplished through excess polycondensation with the Suzuki coupling method.

Entinostat, also known as SNDX-275 and MS-275, is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers.

Ibuproxam is a nonsteroidal anti-inflammatory drug (NSAID).It is the hydroxamic acid of ibuprofen to which it is hydrolyzed in the blood. It was found, that ibuproxam is considerably less damaging to the gastrointestinal tract than is ibuprofen. The analgesic and the antipyretic activities are consistent.

Zibotentan (INN; development code ZD4054) is an experimental anti-cancer drug candidate in development by AstraZeneca. It is an endothelin receptor antagonist.

Fenpropimorph is a morpholine-derived fungicide used in agriculture, primarily on cereal crops such as wheat. It has been reported to disrupt eukaryotic sterol biosynthesis pathways, notably by inhibiting fungal Δ14 reductases. It has also been reported to inhibit mammalian sterol biosynthesis by affecting lanosterol demethylation. Although used in agriculture for pest management purposes, it has been reported to have a strong adverse effect on sterol biosynthesis in higher-plants by inhibiting the cycloeucalenol-obtusifoliol isomerase. This inhibition was shown to not only alter the lipid com

1,4-Bis(trichloromethyl)benzene is an organic compound with the formula C6H4(CCl3)2. A white solid, it is prepared industrially by chlorination of para-xylene. It reacts with terephthalic acid to give terephthaloyl chloride, a precursor to Kevlar. It also reacts with sulfur dioxide to give the same acid chloride and thionyl chloride. It reacts with hydrogen fluoride in 1,2-dichloroethane to form 1,4-bis(chlorodifluoromethyl)benzene in a yield of 79%.

chemical compound

chemical compound

Samatasvir (IDX-719) is an experimental drug for the treatment of hepatitis C. It was originally developed by Idenix, and development has been continued by Merck & Co. following their acquisition of Idenix. Samatasvir has shown good results in Phase II trials.

[2.2]Paracyclophane is a cyclophane that is applied in bio- and materials science. It was first synthesized by Brown and Farthing in 1949 by pyrolyzing para-xylene in the gas phase under low pressure.