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ibuproxam

Structure via PubChem · Public domain (PubChem)

EntityQ3791611· pop 8· linked from 278 articles

Also known as p-Isobutylhydratropohydroxamic acid

Ibuproxam is a nonsteroidal anti-inflammatory drug (NSAID).It is the hydroxamic acid of ibuprofen to which it is hydrolyzed in the blood. It was found, that ibuproxam is considerably less damaging to the gastrointestinal tract than is ibuprofen. The analgesic and the antipyretic activities are consistent.

In the Vinony graph

Vinony's link graph records 278 inbound references to ibuproxam, and connects out to salicylic acid, metamizole sodium and clonixin.

Vinony files it under Drugboxes which contain changes to verified fields, Drugboxes which contain changes to watched fields and Drugs with no legal status.

Vinony links it to 7 Wikipedia language editions.

Chemical data

Formula
C13H19NO2
Molecular weight
221.29 g/mol
IUPAC name
N-hydroxy-2-[4-(2-methylpropyl)phenyl]propanamide
SMILES
CC(C)CC1=CC=C(C=C1)C(C)C(=O)NO
InChIKey
BYPIURIATSUHDW-UHFFFAOYSA-N
XLogP
2.8
Polar surface area
49.3 Ų
H-bond donors
2
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
rheumatic disease

via ChEMBL · EBI

Research

21 papers

via PubMed

Wikidata facts

Mass
221.142
Has use
medication
Show 5 more facts
chemical formula
C₁₃H₁₉NO₂
canonical SMILES
CC(C)CC1=CC=C(C=C1)C(C)C(=O)NO
World Health Organisation international non-proprietary name
ibuproxam
Commons category
Ibuproxam
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

Ibuproxam is a nonsteroidal anti-inflammatory drug (NSAID).It is the hydroxamic acid of ibuprofen to which it is hydrolyzed in the blood. It was found, that ibuproxam is considerably less damaging to the gastrointestinal tract than is ibuprofen. The analgesic and the antipyretic activities are consistent.

==References==

Excerpted from Wikipedia’s “ibuproxam” article, available under the CC BY-SA 4.0 licence.

Available in 7 languages

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