SRI International

American scientific research institute (founded 1946)

1968 computer demonstration by Douglas Engelbart

Bexarotene, sold under the brand Targretin, is an antineoplastic (anti-cancer) agent used for the treatment of cutaneous T cell lymphoma (CTCL). It is a third-generation retinoid.

Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an antiviral drug which is active against herpes simplex and varicella zoster viruses.

Pralatrexate, sold under the brand name Folotyn, is a medication used for the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL).

Halofantrine is a drug used to treat malaria. Halofantrine's structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown, although a crystallographic study showed that it binds to hematin in vitro, suggesting a possible mechanism of action. Halofantrine has also been shown to bind to plasmepsin, a haemoglobin degrading enzyme unique to the malarial parasites.

general-purpose mobile robot

statistical method

Zylon (IUPAC name: 'poly(p-phenylene-2,6-benzobisoxazole)') is a trademarked name for a range of thermoset liquid-crystalline polyoxazole. This synthetic polymer material was invented and developed by SRI International in the 1980s and manufactured by Toyobo. In generic usage, the fiber is referred to as PBO.

chemical compound

InterNIC, known as the Network Information Center (NIC) until 1993, was the organization primarily responsible for Domain Name System (DNS) domain name allocations and X.500 directory services. From its inception in 1972 until October 1, 1991, it was run by the Stanford Research Institute, now known as SRI International, and led by Jake Feinler. From October 1991 until September 18, 1998, it was run by Network Solutions. Thereafter, the responsibility was assumed by the Internet Corporation for Assigned Names and Numbers (ICANN).

Tamibarotene (brand name: Amnolake), also called retinobenzoic acid, is orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity against acute promyelocytic leukaemia (APL) . It is currently marketed only in Japan and early trials have demonstrated that it tends to be better tolerated than ATRA. Tamibarotene has been tested in many other cancer types, including Acute Myeloid Leukemia where it shows no benefit, and lung cancer, where it accelerated the cancer growth and increased mortality.

observatory

radio telescope in California

research facility in western Greenland

Tirapazamine (SR-4233, WIN 59075) is an experimental anticancer drug that is activated to a toxic radical only at very low levels of oxygen (hypoxia). Such levels are common in human solid tumors, a phenomenon known as tumor hypoxia. Thus, tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by radiotherapy and most anticancer drugs. Thus the combination of tirapazamine with conventional anticancer treatments is particularly effective. , tirapazamine is undergoing phase III testing in patients with head

Created and lead by Douglas Engelbart in the sixties. Bootstrapped a one-computer World Wide Web, called NLS, designed to Augment Human Intellect though structure and collaboration.