vidarabine
Sign in to saveAlso known as CI-673, Vira-A®, 2-(6-AMINO-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol, 9-beta-D-Arabinofuranosyl-9H-purin-6-amine, 9-beta-D-arabinofuranosyl-adenine, 9-beta-D-Arabinofuranosyladenine, 9-β-D-arabinofuranosyl-9H-purin-6-amine, 9-β-D-arabinofuranosyladenine
Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an antiviral drug which is active against herpes simplex and varicella zoster viruses.
Research
5,777 papers- Vidarabine is neither a potent nor a selective AC5 inhibitor.Biochemical pharmacology · 2014
- Vidarabine: a preliminary review of its pharmacological properties and therapeutic use.Drugs · 1980
- Vidarabine encephalopathy.Journal of neurology, neurosurgery, and psychiatry · 1984
- An Enzymatic Flow-Based Preparative Route to Vidarabine.Molecules (Basel, Switzerland) · 2020
- Vidarabine (Vira-A).The Medical letter on drugs and therapeutics · 1977
via PubMed
Wikidata facts
- Mass
- 267.097
- Has use
- medication
Show 6 more facts
- Commons category
- Vidarabine
- chemical formula
- C₁₀H₁₃N₅O₄
- medical condition treated
- herpes simplex virus keratitis
- canonical SMILES
- C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O
- isomeric SMILES
- C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O
- subject has role
- antimetabolite
via Wikidata · CC0
~8 min read
Encyclopedic overview
11 sectionsContents
- Medical use
- Selectivity
- Clinical indication
- Pharmacokinetics
- Mode of action
- Mode of resistance
- Discovery
- Synthesis
- Chemical synthesis
- Biosynthesis
- References
Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an antiviral drug which is active against herpes simplex and varicella zoster viruses.
== Medical use == === Selectivity ===
Excerpted from Wikipedia’s “vidarabine” article, available under the CC BY-SA 4.0 licence.