Category

T cells

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type of lymphocyte

type of immune cell

cytotoxic T cell

T-cell receptor

molecule found on the surface of some immune cells

cell-mediated immunity

immune response that does not involve antibodies

thumb|Image of CD4 co-receptor binding to MHC (Major Histocompatibility Complex) non-polymorphic region.

chimeric antigen receptor

artificial T-cell receptor for use in immunotherapy

C-C motif chemokine receptor 5

C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines.

regulatory T cell

cytotoxic T-lymphocyte associated protein 4

mammalian protein found in Homo sapiens

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). Along with the TCR, the CD8 co-receptor plays a role in T cell signaling and aiding with cytotoxic T cell-antigen interactions.

T helper 17 cell

subset of helper-effector T-lymphocytes which synthesize and secrete interleukins IL-17, IL-17F and IL-22

natural killer T cell

group of T cells that share properties of both T cells and natural killer (NK) cells

protein complex and T cell co-receptor

gamma delta T cell

T follicular helper cell

subset of CD4+ T lymphocytes, found in secondary lymphoid organs

Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels.

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a cytoplasmatic protein encoded by gene PTPN22 and a member of PEST family of protein tyrosine phosphatases. This protein is also called "PEST-domain Enriched Phosphatase" ("PEP") or "Lymphoid phosphatase" ("LYP"). The name LYP is used strictly for the human protein encoded by PTPN22, but the name PEP is used only for its mouse homolog. However, both proteins have similar biological functions and show 70% identity in amino acid sequence. PTPN22 functions as a negative regulator of T cell receptor (TCR) signaling, which maintains hom

mucosal associated invariant T cell