1,4,7-triazonane
Sign in to saveAlso known as tacn, 1,4,7-triazacyclononane, [9]aneN₃
1,4,7-Triazacyclononane, known as "TACN" which is pronounced "tack-en," is an aza-crown ether with the formula (C2H4NH)3. TACN is derived, formally speaking, from cyclononane by replacing three equidistant CH2 groups with NH groups. TACN is one of the oligomers derived from aziridine, C2H4NH. Other members of the series include piperazine, C4H8(NH)2, and the cyclic tetramer 1,4,7,10-tetraazacyclododecane.
Wikidata facts
- Mass
- 129.126597
Show 3 more facts
- Commons category
- 1,4,7-Triazacyclononane
- canonical SMILES
- C1CNCCNCCN1
- chemical formula
- C₆H₁₅N₃
Sources (2)
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Encyclopedic overview
4 sectionsContents
- Synthesis
- Coordination chemistry
- Illustrative complexes
- References
1,4,7-Triazacyclononane, known as "TACN" which is pronounced "tack-en," is an aza-crown ether with the formula (C2H4NH)3. TACN is derived, formally speaking, from cyclononane by replacing three equidistant CH2 groups with NH groups. TACN is one of the oligomers derived from aziridine, C2H4NH. Other members of the series include piperazine, C4H8(NH)2, and the cyclic tetramer 1,4,7,10-tetraazacyclododecane.
==Synthesis== The ligand is prepared from diethylene triamine as follows by macrocyclization using ethyleneglycol ditosylate. H2NCH2CH2NHCH2CH2NH2 + 3 TsCl → Ts(H)NCH2CH2N(Ts)CH2CHH2N(H)Ts + 3 HCl Ts(H)NCH2CH2N(Ts)CH2CH2N(H)Ts + 2 NaOEt → Ts(Na)NCH2CH2N(Ts)CH2CH2N(Na)Ts Ts(Na)NCHH2CH2N(Ts)CH2CH2N(Na)Ts + TsOCH2CH2OTs + → [(CH2CH2N(Ts)]3 + 2 NaOTs [(CH2CH2N(Ts)]3 + 3 H2O → [CH2CH2NH]3 + 3 HOTs
Excerpted from Wikipedia’s “1,4,7-triazonane” article, available under the CC BY-SA 4.0 licence.