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1,4-butanediol

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EntityQ161521· pop 29· linked from 819 articles

1,4-butanediol

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Also known as 1,4-BD, HOCH2CH2CH2CH2OH, HO(CH2)4OH, tetramethylene 1,4-diol, 1,4-butylene glycol, 1,4-tetramethylene glycol, 1,4-dihydroxybutane, butane-1,4-diol

1,4-Butanediol, also called butane-1,4-diol (other names include 1,4-B, BD, BDO, and 1,4-BD), is a primary alcohol and an organic compound with the formula HOCH2CH2CH2CH2OH. It is a colorless viscous liquid first synthesized in 1890 via acidic hydrolysis of N,N'-dinitro-1,4-butanediamine by Dutch chemist Pieter Johannes Dekkers, who called it "tetramethylene glycol".

Chemical data

Formula
C4H10O2
Molecular weight
90.12 g/mol
IUPAC name
butane-1,4-diol
SMILES
C(CCO)CO
InChIKey
WERYXYBDKMZEQL-UHFFFAOYSA-N
XLogP
-0.8
Polar surface area
40.5 Ų
H-bond donors
2
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of
alkanediols
Has part
carbon
Mass
90.068
Autonomy
350
Show 12 more facts
chemical formula
C₄H₁₀O₂
canonical SMILES
C(CCO)CO
density
1.0171
Commons category
1,4-Butanediol
safety classification and labelling
Regulation (EC) No. 1272/2008
melting point
20.1
boiling point
235
surface tension
0.0446
dynamic viscosity
0.0849
flash point
121
pKa
14.5
refractive index
1.446
Sources (5)

via Wikidata · CC0

~8 min read

Encyclopedic overview

12 sections
Contents
  • Synthesis
  • Industrial use
  • Use as a recreational drug
  • Pharmacokinetics
  • Pharmacodynamics
  • Legality
  • 2007 contamination of Bindeez toy
  • 2021 poisoning at Darmstadt Technical University
  • Derivatives
  • See also
  • References
  • External links

1,4-Butanediol, also called butane-1,4-diol (other names include 1,4-B, BD, BDO, and 1,4-BD), is a primary alcohol and an organic compound with the formula HOCH2CH2CH2CH2OH. It is a colorless viscous liquid first synthesized in 1890 via acidic hydrolysis of N,N'-dinitro-1,4-butanediamine by Dutch chemist Pieter Johannes Dekkers, who called it "tetramethylene glycol".

==Synthesis== class=skin-invert-image|thumb|left|380px|Conversion of butane to butanediol or butyrolactone via oxidation to maleic anhydride followed by hydrogenation over copper chromite.

Excerpted from Wikipedia’s “1,4-butanediol” article, available under the CC BY-SA 4.0 licence.

Gallery (7)