Structure via PubChem · Public domain (PubChem)
1,5-i-aedans
Sign in to saveAlso known as N-iodoacetyl-N'-(5-sulfonic-1-napthyl)ethylene-diamine, I-AED, IAEDANS, N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine, N-(Iodoacetylaminoethyl)-5-naphthylamine-1-sulfonic acid
IAEDANS is an organic fluorophore (fluorescent molecule). It stands for 5-({2-[(iodoacetyl)amino]ethyl}amino)naphthalene-1-sulfonic acid. It is widely used as a marker in fluorescence spectroscopy.
Chemical data
- Formula
- C14H15IN2O4S
- Molecular weight
- 434.25 g/mol
- IUPAC name
- 5-[2-[(2-iodoacetyl)amino]ethylamino]naphthalene-1-sulfonic acid
- SMILES
- C1=CC2=C(C=CC=C2S(=O)(=O)O)C(=C1)NCCNC(=O)CI
- InChIKey
- ZMERMCRYYFRELX-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 104 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
267 papers- Inactivation of firefly luciferase with N-(iodoacetyl)-N'- (5-sulfo-1-naphthyl)ethylenediamine (I-AEDANS).Archives of biochemistry and biophysics · 1997
- Affinity labeling of phosphoenolpyruvate carboxykinase with 1, 5-I-AEDANS.Biochemical and biophysical research communications · 1979
- Fluorescence-based peptide labeling and fractionation strategies for analysis of cysteine-containing peptides.Analytical chemistry · 2005
- N-Iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine modification of myosin from chicken gizzard.Journal of biochemistry · 1985
- Probe studies of the MgADP state of muscle cross-bridges: microscopic and wavelength-dependent fluorescence polarization from 1,5-IAEDANS-labeled myosin subfragment 1 decorating muscle fibers.Biochemistry · 1987
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 433.979726
Show 3 more facts
- chemical formula
- C₁₄H₁₅IN₂O₄S
- canonical SMILES
- C1=CC2=C(C=CC=C2S(=O)(=O)O)C(=C1)NCCNC(=O)CI
- subject has role
- fluorophore
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Chembox | verifiedrevid = 443867178 | ImageFile=5-((2-(2-iodoacetamido)ethyl)amino)naphthalene-1-sulfonic_acid_200.svg | ImageSize=200px | PIN=5-{[2-(2-Iodoacetamido)ethyl]amino}naphthalene-1-sulfonic acid | OtherNames=5-[2-[(2-Iodo-1-oxoethyl)amino]ethylamino]-1-naphthalenesulfonic acid1,5-IAEDANS |Section1= |Section2= |Section3= }}
IAEDANS is an organic fluorophore (fluorescent molecule). It stands for 5-({2-[(iodoacetyl)amino]ethyl}amino)naphthalene-1-sulfonic acid. It is widely used as a marker in fluorescence spectroscopy.
Excerpted from Wikipedia’s “1,5-i-aedans” article, available under the CC BY-SA 4.0 licence.